Non-isotopic Labeling Reagents and Kits
Enzo Life Sciences MK-2206 2HCl (5mg). CAS: 1032350-13-2
MK-2206 is a highly selective inhibitor of Akt1, Akt2 and Akt3 with IC50 of 8 nM, 12 nM and 65 nM, respectively. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO (14mg/ml) or ethanol (1mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences mTOR inhibitor WYE-23 (5mg). CAS: 1062169-46-3
Alternative name: 4-{6-[4-(3-Cyclopropyl-ureido)-phenyl]-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl}-piperidine-1-carboxylic acid methyl ester. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -80°C.
Enzo Life Sciences WYE-132 (1mg). CAS: 1144068-46-1
A highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Shows an anti-proliferative activity against a variety of tumor cell lines. WYE-132 causes inhibition of protein synthesis and cell size, induction of apoptosis, and cell cycle progression. Alternative name: 1-{4-[1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-phenyl}-3-methyl-urea, WYE-125132. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -80°C.
Agilent Technologies GLYKO INSTANTPC HMN IGG N-LNKD
Glyko InstantPC Human IgG N-Linked Glycan Library [GKPC-005] Glyko InstantPC-(Human IgG N-Linked Glycan Library) The Glyko InstantPC Human IgG N-Linked
Enzo Life Sciences VDM-11 (50mg). CAS: 313998-81-1
Selective and potent inhibitor of the anandamide membrane transporter (AMT) (neuronal (C6 glioma cells): IC50=11µM; non-neuronal (rat RBL-2H3 cells): IC50=7.2µM) with negligible action at TRPV1 and weak action at CB1 receptor (CB1: Ki=5µM; CB2: Ki>5µM) and FAAH (IC50=3.7µM/ IC50>50µM (N18TG2 cell membranes). Alternative name: N-Arachidonoyl-4-hydroxy-2-methylaniline, N-(4-Hydroxy-2-methylphenyl)arachidonoylamide. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (1.5mg/ml) or ethanol (1mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences PD0325901, (10mg), CAS Number: 391210-10-9
Selective MEK inhibitor. PD0325901 (PD325901) is selective and non ATP-competitive MEK inhibitor with an IC50 of 0.33 nM, roughly 500-fold more potent than CI-1040 on the phosphorylation of ERK1 and ERK2. Alternative Name: (R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide. Formula: C16H14F3IN2O4. MW: 482.2. CAS Number: 391210-10-9. Purity: ≥99% (HPLC). Appearance: White to off-white powder. Solubility: Soluble in DMSO (96mg/ml) or ethanol (40mg/ml). Long Term Storage: -20°C
Enzo Life Sciences GF109203X (5mg). CAS: 133052-90-1
Potent and selective protein kinase C inhibitor which has been used effectively in platelets, Swiss 3T3 fibroblasts and macrophages. Inhibitory profile: PKC, IC50=0.02µM (inhibits α, ßI, ßII and γ subtypes with similar potency); PKA, IC50=2.0µM; phosphorylase kinase, IC50=0.7µM; insulin, EGF and PDGF receptor tyrosine kinases are not inhibited at concentrations up to 50µM. Alternative name: 2-[1-(3-Dimethylaminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide, Bisindolylmaleimide I. Purity: ≥98% (HPLC). Solubility: Soluble in dimethyl formamide or DMSO (10mg/ml, warm to 40°C and vortex well). . Long Term Storage: -20°C.
Enzo Life Sciences PI 3K-SH2-OMT (0.5 mg)
This unique SH2 domain ligand is derived from the sequence flanking Tyr751 of the PDGF receptor. It inhibits the PI 3-kinase p85 C-terminal SH2 domain (IC50=14.2 µM). It contains the nonhydrolyzable phosphotyrosine mimetic L-O-(2-malonyl)tyrosine (OMT) and is provided as the trimethyl ester for greater cell permeability. Purity: ≥98% (TLC). Formulation: Lyophilized. Solubility: Soluble in DMSO (0.5 mg/ml) or ethanol (0.3 mg/ml). Long Term Storage: -20°C.
Enzo Life Sciences LPS from Salmonella abortus equi S-form (TLRGRADE™) (Ready-to-Use) (Biotin) (500µl)
Useful reagent for evaluating LPS binding and cell activation in white blood cells. Alternative name: Lipopolysaccharide from Salmonella abortus equi S-form. Formulation: Liquid. Sterile, ready-to-use solution in pyrogen-free double-distilled water. Purity: Absence of dectectable protein or DNA contaminants with agonistic TLR activity. Long Term Storage: +4°C.
Enzo Life Sciences LPS from Salmonella enteritidis S-Form (TLRGRADE™) (Ready-to-Use) (2ml)
Alternative name: Lipopolysaccharide from Salmonella enteritidis S-Form. Formulation: Liquid. Sterile, ready-to-use solution in pyrogen-free double distilled water. Purity: Absence of detectable protein or DNA contaminants with agonistic TLR activity. Long Term Storage: +4°C.
Enzo Life Sciences MMP-13 inhibitor (1mg). CAS: 544678-85-5
Alternative name: PB4, N4,N6-Bis(4-fluoro-3-methylbenzyl)pyrimidine-4,6-dicarboxamide, Pyrimidine-4,6-dicarboxylic acid, bis-(4-fluoro-3-methyl-benzylamide), 4-N,6-N-bis[(4-fluoro-3-methylphenyl)methyl]pyrimidine-4,6-dicarboxamide. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -80°C.
Enzo Life Sciences C5a receptor antagonist W-54011 (5mg). CAS: 405098-33-1
Alternative name: N-((4-Dimethylaminophenyl)methyl)-N-(4-isopropylphenyl)-7-methoxy-1,2,3,4-tetrahydronaphthalen-1-carboxamide . HCl. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO or methanol. Long Term Storage: -80°C.
Enzo Life Sciences PD 173074 (10mg). CAS: 219580-11-7
A cell-permeable compound that acts as a potent, ATP-competitive, and reversible inhibitor of FGF and VEGF receptors. PD 173074 inhibits PDGFR and c-Src only at much higher concentration. Shown to inhibit the autophosphorylation of endogenous FGFR1 and overexpressed VEGFR2. Alternative name: 1-t-Butyl-3-(6-(3,5-dimethoxyphenyl)-2-(4-diethylaminobutylamino)-pyrido[2,3-d]pyrimidin-7-yl)urea. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO or methanol. Long Term Storage: -80°C.
Enzo Life Sciences Purvalanol A (5mg). CAS: 212844-53-6
Inhibitor of human CDK1 (IC50=4nM), CDK2/cyclin A (IC50=70nM), Cdc2/cyclin B, CDK2/cyclin E (IC50=35nM), CDK4/cyclin D1 (IC50=850nM) as well as CDK5/p35 (IC50=75nM). More membrane permeable than purvalanol B. Alternative name: 6-[(3-Chloro)anilino]-2(1R)-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine. Formula: C19H25N6OCl. MW: 388.9. Purity: ≥99% (NMR). Solubility: Soluble in DMSO, methanol or dichloromethane. Long Term Storage: -20°C. Handling: Keep under inert gas. Keep cool and dry.
Enzo Life Sciences TG100-115 (10mg). CAS: 677297-51-7
Alternative name: 6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -80°C.